Model NO.: 78246-49-8
Molecular Formula: C21h30o3
Molecular Weight: 330.645
Melting Point: 447.571c
Flash Point: 194.228
Density: 1.117 g/cm3
Leading Time: Within 12hours After Payment
Delivery Time: Within 5woking Days After Payment
Usage: Pharmaceutical Material
Synonyms: Acetic Acid 3-Oxo-7-Methylestra
Trademark: JZY
Transport Package: Discreet Package
Specification: White Powder
Origin: China
HS Code: 2942000000
Model NO.: 78246-49-8
Molecular Formula: C21h30o3
Molecular Weight: 330.645
Melting Point: 447.571c
Flash Point: 194.228
Density: 1.117 g/cm3
Leading Time: Within 12hours After Payment
Delivery Time: Within 5woking Days After Payment
Usage: Pharmaceutical Material
Synonyms: Acetic Acid 3-Oxo-7-Methylestra
Trademark: JZY
Transport Package: Discreet Package
Specification: White Powder
Origin: China
HS Code: 2942000000
Product Description:
Name:AICAR
CAS:2627-69-2
EINECS:220-097-5
Molecular Formula:C9H14N4O5
Molecular Weight:258.23
Apperance: White or off-white powder.
Description:
1.AICAR is a peptide whose technical name is 5-Aminoimidazole-4-carboxamide ribonucleotide.It can also be known as AICA ribonucleotide, ZMP, or Acadesine.It is an intermediate contained in the generation of inosine monophosphate.It primarily functions as an AMP-activated protein kinase agonist, meaning that it has the ability to promote the operation of nutrient stores for energy production.
2.AICAR is an adenosine analog that selectively activates AMP-activated protein kinase (AMPK). AMPK regulates lipid and glucose metabolism to maintain cellular energy homeostasis (Hardie and Carling).
AICAR can play a hand in boosting these processes because it contains the ability to penetrate cardiac cells and block the production of enzymes tied to regulating glucose intake and energy expulsion.
3.With these regulatory enzymes inhibited, the affected cells can in turn boost the amount of glucose that can be received, and it can also increase its level of energy conversion.Additionally, the peptide's presence has been determined to aid in lowering programmed cell death, a process that is also known as apoptosis.
Functions:
1.AICAR (AICA-Riboside) strongly inhibits the transcription of PPAR&alpha and the coactivation of PPAR&alpha. In adipocyte studies it has been shown to antagonize lipolysis induced by isoprenaline and has been suggested for use in kinase cascade research. Additionally, research indicates that AICAR blocks the differentiation of 3T3-L1 (sc-2243) adipocytes.
2.Studies demonstrate that AICAR can mimic the activity of insulin (sc-211647) by activating AMPK (AMP-activated protein kinase), and affecting the expression of PEPCK-M (PEPCK) and glucose-6-phosphatase (G6Pase).
3.The 5-aminoimidazole-4-carboxamide ribonucleoside (ZMP) is the monophosphorylated derivative of AICA-Riboside, and it can serve as the substrate for the aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC). AICAR is an inhibitor of Hsp90, mTOR and p70 S6 Kinase.
About US:
Is one of the reliable and professional suppliers and  exporters in this field for many years. Our target market is a health and fitness conscious individual who wants to embark on or develop a professional career within the health and fitness industry,Our expectations are to promote Advanced Body Nutrition , our athletes, and our sponsors to the best of our ability while becoming internationally known as a reputable and conscientious corporation
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Our Service:
1. Fast Delivery: We can delivery within 24 hours upon receipt of your payment.
2. Quality can be promised. Hot sell to Worldwide.
3. Payment Terms: T/T Bank Transfer, Western Union and MoneyGram Available.
4. Free Sample available at any time.
5. Tracking your order at any time. Inform your order's further new situation at any time.
6. Package: Professional packing with professional materials.
Â
After-sales service:
1 Reship Policy:Reship for 70% for missing or seized order
2 Discount:5% discount for second same order
Product Description:
Name:AICAR
CAS:2627-69-2
EINECS:220-097-5
Molecular Formula:C9H14N4O5
Molecular Weight:258.23
Apperance: White or off-white powder.
Description:
1.AICAR is a peptide whose technical name is 5-Aminoimidazole-4-carboxamide ribonucleotide.It can also be known as AICA ribonucleotide, ZMP, or Acadesine.It is an intermediate contained in the generation of inosine monophosphate.It primarily functions as an AMP-activated protein kinase agonist, meaning that it has the ability to promote the operation of nutrient stores for energy production.
2.AICAR is an adenosine analog that selectively activates AMP-activated protein kinase (AMPK). AMPK regulates lipid and glucose metabolism to maintain cellular energy homeostasis (Hardie and Carling).
AICAR can play a hand in boosting these processes because it contains the ability to penetrate cardiac cells and block the production of enzymes tied to regulating glucose intake and energy expulsion.
3.With these regulatory enzymes inhibited, the affected cells can in turn boost the amount of glucose that can be received, and it can also increase its level of energy conversion.Additionally, the peptide's presence has been determined to aid in lowering programmed cell death, a process that is also known as apoptosis.
Functions:
1.AICAR (AICA-Riboside) strongly inhibits the transcription of PPAR&alpha and the coactivation of PPAR&alpha. In adipocyte studies it has been shown to antagonize lipolysis induced by isoprenaline and has been suggested for use in kinase cascade research. Additionally, research indicates that AICAR blocks the differentiation of 3T3-L1 (sc-2243) adipocytes.
2.Studies demonstrate that AICAR can mimic the activity of insulin (sc-211647) by activating AMPK (AMP-activated protein kinase), and affecting the expression of PEPCK-M (PEPCK) and glucose-6-phosphatase (G6Pase).
3.The 5-aminoimidazole-4-carboxamide ribonucleoside (ZMP) is the monophosphorylated derivative of AICA-Riboside, and it can serve as the substrate for the aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC). AICAR is an inhibitor of Hsp90, mTOR and p70 S6 Kinase.
About US:
Is one of the reliable and professional suppliers and  exporters in this field for many years. Our target market is a health and fitness conscious individual who wants to embark on or develop a professional career within the health and fitness industry,Our expectations are to promote Advanced Body Nutrition , our athletes, and our sponsors to the best of our ability while becoming internationally known as a reputable and conscientious corporation
Â
Our Service:
1. Fast Delivery: We can delivery within 24 hours upon receipt of your payment.
2. Quality can be promised. Hot sell to Worldwide.
3. Payment Terms: T/T Bank Transfer, Western Union and MoneyGram Available.
4. Free Sample available at any time.
5. Tracking your order at any time. Inform your order's further new situation at any time.
6. Package: Professional packing with professional materials.
Â
After-sales service:
1 Reship Policy:Reship for 70% for missing or seized order
2 Discount:5% discount for second same order
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